教員情報 - 北浦　靖之

キタウラ　ヤスユキ KITAURA Yasuyuki
北浦　靖之

所属応用生物学部食品栄養科学科

臨地実習推進部管理栄養実習センター

大学院応用生物学研究科応用生物学専攻

職名教授

著書・論文歴
論文	The synergistic synbiotic potential of 1-kestose and Bifidobacterium longum in the mouse gut JOURNAL OF FUNCTIONAL FOODS 101 2023/02
論文	Branched-chain amino acids regulate hyaluronan synthesis and PPARα expression in the skin. Bioscience, biotechnology, and biochemistry 85 (11),2292-2294頁 2021/10/21
論文	Supplementation of 1-Kestose Modulates the Gut Microbiota Composition to Ameliorate Glucose Metabolism in Obesity-Prone Hosts. Nutrients 13 (9) 2021/08/27
論文	Macrophages rely on extracellular serine to suppress aberrant cytokine production. Scientific reports 11 (1),11137-11137頁 2021/05/27
論文	Antihypertensive drug valsartan as a novel BDK inhibitor. Pharmacological research 167,105518-105518頁 2021/05
論文	Urinary l-erythro-β-hydroxyasparagine-a novel serine racemase inhibitor and substrate of the Zn2+-dependent d-serine dehydratase. Bioscience reports 41 (4) 2021/04/30
論文	1-Kestose supplementation mitigates the progressive deterioration of glucose metabolism in type 2 diabetes OLETF rats. Scientific reports 10 (1),15674-15674頁 2020/09/24
論文	BDK Deficiency in Cerebral Cortex Neurons Causes Neurological Abnormalities and Affects Endurance Capacity. Nutrients 12 (8) 2020/07/29
論文	Branched-chain amino acid supplementation ameliorates angiotensin II-induced skeletal muscle atrophy. Life sciences 250,117593-117593頁 2020/06/01
論文	Reply to Comment on Watanabe, A.; Kadota, Y.; Yokoyama, H.; Tsuruda, S.; Kamio, R.; Tochio, T.; Shimomura, Y.; Kitaura, Y. Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats. Foods 2020, 9, 4. Foods (Basel, Switzerland) 9 (4) 2020/04/22
論文	Experimental Determination of the Threshold Dose for Bifidogenic Activity of Dietary 1-Kestose in Rats. Foods (Basel, Switzerland) 9 (1) 2019/12/19
論文	Enhanced Echo Intensity of Skeletal Muscle Is Associated With Exercise Intolerance in Patients With Heart Failure. Journal of cardiac failure 26 (8),685-693頁 2019/09/15
論文	Feeding of 1-Kestose Induces Glutathione-S-Transferase Expression in Mouse Liver. Foods (Basel, Switzerland) 8 (2) 2019/02/13
論文	Ca2+-dependent inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate. Biochemical and biophysical research communications 504 (4),916-920頁 2018/10/12
論文	Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions. Pharmacological research 133,215-217頁 2018/07
論文	Branched-chain amino acids regulate type I tropocollagen and type III tropocollagen syntheses via modulation of mTOR in the skin. Bioscience, biotechnology, and biochemistry 82 (4),611-615頁 2018/04
論文	ラットの高脂肪食誘発インスリン抵抗性に対する1-ケストース摂取の影響日本栄養・食糧学会大会講演要旨集 72回,273-273頁 2018/04
論文	Branched-chain amino acid (BCAA) supplementation enhances adaptability to exercise training of mice with a muscle-specific defect in the control of BCAA catabolism. Bioscience, biotechnology, and biochemistry,1-4頁 2018/03/01
論文	Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex. PLoS biology 16 (3),e2005090 2018/03
論文	Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice. Metabolism: clinical and experimental 69,177-187頁 2017/04
論文	Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition. Scientific reports 7 (7),39825-39825頁 2017/01/04
論文	BCAA FUNCTION AND INSULIN RESISTANCE FROM THE STUDIES USING GENETICALLY ENGINEERED MICE IN BCAA CATABOLISM ANNALS OF NUTRITION AND METABOLISM 71,140-140頁 2017
論文	Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism. PloS one 12 (7),e0180989 2017
論文	SPORTS NUTRITION FOR ACTIVE LIFE-STYLE ANNALS OF NUTRITION AND METABOLISM 71,1362-1362頁 2017
論文	Novel mechanism responsible for regulation of branched-chain alpha-ketoacid dehydrogenase kinase FASEB JOURNAL 30 2016/04
論文	運動時の骨格筋でのPGC1αを介したアミノ酸代謝の役割アミノ酸研究 9 (2),117-117頁 2016/03
論文	mTORC1 is involved in the regulation of branched-chain amino acid catabolism in mouse heart. FEBS open bio 6 (1),43-9頁 2016/01
論文	An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. PloS one 11 (11),e0166850 2016
論文	PEGylated D-serine dehydratase as a D-serine reducing agent. Journal of pharmaceutical and biomedical analysis 116,34-9頁 2015/12/10
論文	ヒトECHS1の生化学的解析と軽症型ECHS1欠損症の病態解明日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 88回・38回,[4T特-01(3P1177)]頁 2015/12
論文	Clinical, biochemical and metabolic characterisation of a mild form of human short-chain enoyl-CoA hydratase deficiency: significance of increased N-acetyl-S-(2-carboxypropyl)cysteine excretion. Journal of medical genetics 52 (10),691-8頁 2015/10
論文	軽症Short-chain enoyl-CoA hydratase(ECHS1)欠損症の生化学的解析診断に有効な化合物の同定日本先天代謝異常学会雑誌 31,128-128頁 2015/10
論文	Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. Metabolism: clinical and experimental 64 (9),1157-64頁 2015/09
論文	Endurance Capacity of Muscle-specific Branched-chain alpha-Ketoacid Dehydrogenase (BCKDH) Kinase-deficient Mice FASEB JOURNAL 29 2015/04
論文	Enhanced oleate uptake and lipotoxicity associated with laurate. FEBS open bio 5,485-91頁 2015
論文	Novel Physiological Functions of Branched-Chain Amino Acids. Journal of nutritional science and vitaminology 61 Suppl,S112-4 2015
論文	Regulation of the plasma amino acid profile by leucine via the system L amino acid transporter. Bioscience, biotechnology, and biochemistry 79 (12),2057-62頁 2015
論文	Bolus ingestion of individual branched-chain amino acids alters plasma amino acid profiles in young healthy men. SpringerPlus 3,35-35頁 2014
論文	Clinical and biochemical characterization of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency that causes Leigh-like disease and ketoacidosis. Molecular genetics and metabolism reports 1,455-460頁 2014
論文	Effects of ingesting highly branched cyclic dextrin during endurance exercise on rating of perceived exertion and blood components associated with energy metabolism. Bioscience, biotechnology, and biochemistry 78 (12),2117-9頁 2014
論文	PGC-1α-mediated branched-chain amino acid metabolism in the skeletal muscle. PloS one 9 (3),e91006 2014
論文	Regulation of hepatic branched-chain α-ketoacid dehydrogenase complex in rats fed a high-fat diet. Obesity research & clinical practice 7 (6),e439-44 2013/12
論文	Multispecificity of immunoglobulin M antibodies raised against advanced glycation end products: involvement of electronegative potential of antigens. The Journal of biological chemistry 288 (19),13204-14頁 2013/05/10
論文	Regulation of branched-chain alpha-ketoacid dehydrogenase (BCKDH) kinase by a Mn2+-dependent factor in rat liver mitochondria FASEB JOURNAL 27 2013/04
論文	陰性荷電分子を認識する自然抗体日本生化学会大会(Web) 86th 2013
論文	[Diversity of physiological functions of branched-chain amino acids]. Seikagaku. The Journal of Japanese Biochemical Society 84 (11),938-42頁 2012/11
論文	Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. Atherosclerosis 222 (2),409-16頁 2012/06
論文	Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats. JPEN. Journal of parenteral and enteral nutrition 36 (3),337-43頁 2012/05
論文	個々の分岐鎖アミノ酸摂取によるヒト血漿遊離アミノ酸濃度に及ぼす影響日本栄養・食糧学会大会講演要旨集 66回,124-124頁 2012/04
論文	ロイシンまたはイソロイシン摂取によるヒト血漿遊離アミノ酸組成に及ぼす影響アミノ酸研究 5 (2),101-102頁 2012/03
論文	Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles. European journal of applied physiology 111 (8),1815-28頁 2011/08
論文	ロイシン摂取によるヒト血漿遊離アミノ酸濃度に及ぼす影響日本栄養・食糧学会大会講演要旨集 65回,266-266頁 2011/04
論文	Effects of branched-chain amino acid supplementation on plasma concentrations of free amino acids, insulin, and energy substrates in young men. Journal of nutritional science and vitaminology 57 (1),114-7頁 2011
論文	Regulation of hepatic branched-chain alpha-keto acid dehydrogenase kinase in a rat model for type 2 diabetes mellitus at different stages of the disease. Biochemical and biophysical research communications 393 (2),303-7頁 2010/03/05
論文	The mouse resources at the RIKEN BioResource center. Experimental animals 58 (2),85-96頁 2009/04
論文	Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b. Immunity 26 (5),567-78頁 2007/05
論文	Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins. Immunity 25 (4),571-81頁 2006/10
論文	PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cells. Proceedings of the National Academy of Sciences of the United States of America 103 (2),395-400頁 2006/01/10
論文	The penta-EF-hand protein ALG-2 interacts with a region containing PxY repeats in Alix/AIP1, which is required for the subcellular punctate distribution of the amino-terminal truncation form of Alix/AIP1. Journal of biochemistry 135 (1),117-28頁 2004/01
論文	Structures, functions and molecular evolution of the penta-EF-hand Ca 2+-binding proteins Biochimica et Biophysica Acta - Proteins and Proteomics 1600 (1-2),51-60頁 2002/11/04
論文	Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins. Biochimica et biophysica acta 1600 (1-2),51-60頁 2002/11/04
論文	ALG-2 interacts with the amino-terminal domain of annexin XI in a Ca(2+)-dependent manner. Biochemical and biophysical research communications 291 (5),1166-72頁 2002/03/15
論文	Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions. Archives of biochemistry and biophysics 399 (1),12-8頁 2002/03/01
論文	Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner JOURNAL OF BIOLOGICAL CHEMISTRY 276 (17),14053-14058頁 2001/04
論文	Peflin, a novel member of the five-EF-hand-protein family, is similar to the apoptosis-linked gene 2 (ALG-2) protein but possesses nonapeptide repeats in the N-terminal hydrophobic region Biochemical and Biophysical Research Communications 263 (1),68-75頁 1999/09/16
論文	Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK Proceedings of the National Academy of Sciences of the United States of America 95 (22),13221-13226頁 1998/10/27
論文	Calcium-induced exposure of a hydrophobic surface of mouse ALG-2, which is a member of the penta-EF-hand protein family Journal of Biochemistry 124 (6),1170-1177頁 1998