教員情報 - 田島　織絵

タジマ　オリエ TAJIMA Orie
田島　織絵

所属

生命健康科学部作業療法学科

臨地実習推進部作業療法実習センター

生命健康科学部生命医科学科

大学院生命健康科学研究科生命医科学専攻

職名准教授

著書・論文歴
著書	Chemical Identification of Glycosphingolipid Antigens Recognized by Antibodies. Methods Mol Biol. (3035),123-135頁 (共著) 2026/09
著書	Ganglioside Expression in Melanocytes: Modulation by Intrinsic and Extrinsic Factors Methods Mol Biol. (3035),419-427頁 (共著) 2026/09
論文	GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics. Cancer science 116 (4),862-870 (共著) 2025/04
論文	Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins. International journal of molecular sciences 25 (23) (共著) 2024/11
論文	Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells. Nagoya journal of medical science 86 (3),435-451 (共著) 2024/08
論文	Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene. FEBS open bio 13 (9),1615-1624 (共著) 2023/09
論文	Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas. Scientific reports 13 (1),4987 (共著) 2023/03
論文	Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway. PloS one 18 (2),e0281414 (共著) 2023/02/24
論文	Signaling domains of cancer-associated glycolipids. Glycoconjugate journal 39 (2),145-155 (共著) 2022/04
論文	Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins. International journal of molecular sciences 23 (1) (共著) 2021/12
論文	Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia. Journal of biochemistry 168 (2),103-112 (共著) 2020/08
論文	Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering. International journal of molecular sciences 21 (6) (共著) 2020/03
論文	TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes. Scientific reports 9 (1),14740 (共著) 2019/10
論文	New era of research on cancer-associated glycosphingolipids. Cancer science 110 (5),1544-1551 (共著) 2019/05
論文	Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration - Great progress over the last 70 years. Proceedings of the Japan Academy. Series B, Physical and biological sciences 95 (3),136-149 (共著) 2019/03
論文	Differential roles of gangliosides in malignant properties of melanomas. PloS one 13 (11),e0206881 (共著) 2018/11
論文	Gangliosides in Inflammation and Neurodegeneration. Progress in molecular biology and translational science 156,265-287 (共著) 2018/04
論文	Glycolipids: Essential regulator of neuro-inflammation, metabolism and gliomagenesis. Biochimica et biophysica acta. General subjects 1861 (10),2479-2484 (共著) 2017/10
論文	Regulatory function of glycosphingolipids in the inflammation and degeneration. Archives of biochemistry and biophysics 571,58-65 (共著) 2015/04
論文	Glycosphingolipids in the regulation of the nervous system. Advances in neurobiology 9,307-20 (共著) 2014/09
論文	Ganglioside deficiency causes inflammation and neurodegeneration via the activation of complement system in the spinal cord. Journal of neuroinflammation 11,61 (共著) 2014/03
論文	UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6. Biochemical and biophysical research communications 445 (2),504-10 (共著) 2014/03
論文	Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas. Cancer science 105 (1),52-63 (共著) 2014/01
論文	Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues. Neurochemical research 37 (6),1185-91 (共著) 2012/06
論文	Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides. Cancer science 102 (12),2139-49 (共著) 2011/12
論文	Regulatory mechanisms of nervous systems with glycosphingolipids. Neurochemical research 36 (9),1578-86 (共著) 2011/09
論文	Wisp2/CCN5 up-regulated in the central nervous system of GM3-only mice facilitates neurite formation in Neuro2a cells via integrin-Akt signaling. Biochemical and biophysical research communications 411 (3),483-9 (共著) 2011/08
論文	[Molecular mechanisms for the regulation of nervous systems with glycosphingolipids]. Seikagaku. The Journal of Japanese Biochemical Society 83 (3),169-78 (共著) 2011/03
論文	Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice. Journal of neurochemistry 116 (5),926-35 (共著) 2011/03
論文	Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains. The Journal of biological chemistry 285 (35),27213-27223 (共著) 2010/08
論文	Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice. Behavioural brain research 206 (1),101-8 (共著) 2010/01
論文	Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues. Proceedings of the National Academy of Sciences of the United States of America 106 (52),22405-10 (共著) 2009/12
論文	Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging. Behavioural brain research 198 (1),74-82 (共著) 2009/03
論文	Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: sensitivity analysis with glycosylation-defective mutant mice. Biochemical and biophysical research communications 378 (2),179-81 (共著) 2009/01
論文	Expression and roles of a xenopus head-forming gene homologue in human cancer cell lines. Nagoya journal of medical science 70 (3-4),73-82 (共著) 2008/08
論文	Impaired hypoglossal nerve regeneration in mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms. Glycobiology 18 (7),509-16 (共著) 2008/07
論文	Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21. Journal of neurochemistry 105 (3),1057-66 (共著) 2008/05
論文	Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins. The Journal of biological chemistry 281 (15),10230-5 (共著) 2006/04
論文	Sensory nerve-dominant nerve degeneration and remodeling in the mutant mice lacking complex gangliosides. Neuroscience Vol.135,1167-1178頁 (共著) 2005/09
論文	Over-expression of GM1 enhances cell proliferation with epidermal growth factor without affecting the receptor localization in the microdomain in PC12 cells. Int J Oncol. Vol.26 (共著) 2005/01
論文	Functional analysis of the nervous system in knockout mice of ganglioside synthase genes. [Japanese] Tanpakushitsu Kakusan Koso. Vol.49 (共著) 2004/11
論文	Glycosphingolipids in engineered mice: insights into function. Semin Cell Dev Biol. Vol.15 (共著) 2004/08
論文	Nutritional assessment of elderly Japanese nursing home residents of differing mobility using anthropometric measurements, biochemical indicators and food intake. Geriatrics and Gerontology International Vol.4 (共著) 2004/04
論文	Two new potent and convenient predictors of mortality in older nursing home residents in Japan. Geriatrics and Gerontology International Vol.4 (共著) 2004/04
論文	No sex-linked inheritance of longevity between Japanese centenarians and their relatives. J Am Geriatr Soc Vol.52 (共著) 2004/03
論文	骨とビタミンD受容体遺伝子多型．臨床スポーツ医学 Vol.20 (共著) 2003/01
論文	Potential role of vitamin D receptor gene polymorphism to bone phenotypes in young male athletes. J. Appl. Physiol. Vol.283 (共著) 2002/12
論文	GE, SI and EGP of exercise-trained middle-aged men estimated by a 2-compartment labeled minimal model. Am. J. Physiol. Vol.283 (共著) 2002/10
論文	Contribution of vitamin D receptor genotypes to bone mineral density in young male athletes with different impact loading. Eur. J. Sport Sci. Vol. 2 (共著) 2002/02
論文	高齢者の健康・体力づくりの基本 GERONTOLOGY Vol.14 2002
論文	Genetic markers of physical performance. Bull.Inst. Health & Sport Sci. Vol.24 2001
論文	運動能力の素質に関連する遺伝子— チャンピオンの遺伝子— 筑波大学体育科学系紀要 Vol.24 2001
論文	骨密度の違いとビタミンＤ受容体遺伝子体育の科学 Vol.51 2001
論文	Interaction of the effects between vitamin D receptor polymorphism and exercise training on bone metabolism. J. Appl. Physiol. Vol.88 (共著) 2000/04