教員情報 - 西沢　祐治

ニシザワ　ユウジ NISHIZAWA Yuji
西沢　祐治

所属生命健康科学部生命医科学科

臨地実習推進部臨床検査技術教育・実習センター

大学院生命健康科学研究科生命医科学専攻

職名教授

著書・論文歴
著書	角膜移植後、創傷治癒過程にある角膜におけるコンドロイチン硫酸の局所発現について CONNECTIVE TISSUE 31 (2),96 (共著) 1999
著書	新しい光学顕微鏡　第二巻「共焦点レーザー顕微鏡の医学・生物学への応用」　第三章　4. 細胞内構造の観察への応用,96-102頁 (共著) 1995
著書	Involvement of protein kinase C in the control of cell-cell and cell-matrix junctions in relation to differentiation of keratinocytes. The biology of the epidermis, Akira Ohkawara and Joseph McGuire, editors,85-95頁 (共著) 1992
著書	シグナル伝達と表皮細胞の増殖, 分化とECM受容体 CONNECTIVE TISSUE 23,29 (共著) 1991
著書	表皮細胞における細胞外基質受容体（ヘミデスモソーム蛋白とインテグリン）とその制御. 厚生省特定疾患強皮症調査研究班 (共著) 1991
論文	A rat model for retinitis pigmentosa with rapid retinal degeneration enables drug evaluation in vivo. Biol Proced Online. 23 (1),11 (共著) 2021/06/04
論文	Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift. Cell Mol Biol Lett.,25-40頁 (共著) 2020/08/24
論文	Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+ leukemia cells. Biochem Biophys Res Commun. 525 (4),1074-1080頁 (共著) 2020/05/14
論文	Genome-wide association study and whole-genome sequencing identify a deletion in LRIT3 associated with canine congenital stationary night blindness. Biochem Biophys Res Commun. 9 (1) (共著) 2019/10/02
論文	BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells. Biochemistry and Biophysics Reports. 15,69-75頁 (共著) 2018/07/02
論文	Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR. Biochemical and Biophysical Research Communications. 486 (2),551-557頁 (共著) 2017/04/29
論文	Malondialdehyde induces autophagy dysfunction and VEGF secretion in the retinal pigment epithelium in age-related macular degeneration. Free Radic Biol Med. 94,121-134頁 (共著) 2016/02/23
論文	A Naturally Occurring Canine Model of Autosomal Recessive Congenital Stationary Night Blindness. PloS One 10 (9),e0137072 (共著) 2015/09
論文	Isolation of a hemidesmosome-rich fraction from a human squamous cell carcinoma cell line. Exp Cell Res. 324 (2),172-82頁 (共著) 2014/01/10
論文	Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: comparison with brain tau. Biochim Biophys Acta. 1832 (10),1549-59頁 (共著) 2013/10
論文	Identification of Autoantibodies against TRPM1 in Patients with Paraneoplastic Retinopathy Associated with ON Bipolar Cell Dysfunction. PLoS ONE 2011 May6 (5) (共著) 2011/05
論文	Serotonin Augments Gut Pacemaker Activity via 5-HT(3) Receptors. PLoS One. 6 (9),e24928. (共著) 2011
論文	Rac is involved in the interkinetic nuclear migration of cortical progenitor cells. Neuroscience Research. 63 (4),294-301頁 (共著) 2009/04
論文	Generation of a Transgenic Rabbit Model of Retinal Degeneration. Investigative Ophthalmology and Visual Sciences (50),1371-7頁 (共著) 2009/03
論文	The Unfolded Protein Response Is Activated in Differentiating Epidermal Keratinocytes. Journal of Investigative Dermatology 12 (共著) 2009/03
論文	Photopic Electroreinograms of mGluR6-Deficient Mice. Current Eye Research. 2008 (33),91-99頁 (共著) 2008
論文	LEDGF/DFS70, a Major Autoantigen of Atopic Dermatitis, Is a Component of Keratohyalin Granules. J Investigative Dermatology. 127 (1),75-80頁 (共著) 2007/01
論文	Pax6 transcription factor regulates interkinetic nuclear movement in cortical progenitor cells via centrosomal stabilization. Genes to Cells. 2007 (12),983-996頁 (共著) 2007
論文	Survey of the morphogenetic dynamics of the ventricular surface of the developing mouse neocortex. Developmental Dynamics. 2007 (236),3061-3070頁 (共著) 2007
論文	Close Interrelationship of Sphingomyelinase and Caveolin in Triton X-100-insoluble Membrane Microdomains. Sphingolipid Biology,233-244頁 (共著) 2006
論文	Both type-I hemidesmosomes and adherens-type junctions contribute to the cell-substratum adhesion system in myoepithelial cells. Eur J Cell Biol. 84 (2-3.),407-15頁 (共著) 2005/03
論文	Role of apoptosis controlled by cytochrome c released from mitochondria for luteal function in human granulosa cells. Am J Reprod Immunol. 53 (3),144-52頁 (共著) 2005/03
論文	Effect of plasmin on laminin and fibronectin during plasmin-assisted vitrectomy. Arch Ophthalmol. 123 (2),209-13頁 (共著) 2005/02
論文	Modern slice culture for direct observation of production and migration of brain neurons. Nagoya Journal of Medical Science. 67,65-70頁 (共著) 2005
論文	Physiological function of S-cone system is not enhanced in rd7 mice. Exp Eye Res. 2005 (81),751-758頁 (共著) 2005
論文	Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility. J Cell Sci. 2005 (118),4163-73頁 (共著) 2005
論文	The switch mechanism of the cell death mode from apoptosis to necrosis in menadione-treated human osteosarcoma cell line 143B cells. Microsc Res Tech. 64,255-268頁 (共著) 2004
論文	Characterization of mammalian synemin, an intermediate filament protein present in all four classes of muscle cells and some neuroglial cells: co-localization and interaction with type III intermediate filiament proteins and keratins. Cell Tissue Res 313,195-207頁 (共著) 2003
論文	The 97-kDa (LABD97) and 120-kDa (LAD-1) fragments of bullous pemphigoid antigen 180/type XVII collagen have different N-termini. Journal of Investigative Dermatology. 121,1554-1556頁 (共著) 2003
論文	Ultrastructural basis for the transition of cell death mode from apoptosis to necrosis in menadione-treated osteosarcoma 143B cells. J Electron Microsc (Tokyo) 52,313-325頁 (共著) 2003
論文	Mechanism of leflunomide-induced proliferation of mitochondria in mammalian cells. Mitochondrion 2,163-179頁 (共著) 2002
論文	Phosphorylation of cytokeratin 17 by herpes simplex virus type 2 US3 protein kinase. Microbiology and Immunology 46,707-719頁 (共著) 2002
論文	Opposite effects of microtubule-stabilizing and microtubule-destabilizing drugs on biogenesis of mitochondria in mammalian cells. Journal of Cell Science 114,281-291頁 (共著) 2001
論文	Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus. Cell Tissue Res 305,107-114頁 (共著) 2001
論文	Direct imaging of phosphorylation-dependent conformational change and DNA binding of CREB by electron microscopy. Gene to Cell 5,515-522頁 (共著) 2000
論文	Functional aspects of megamitochondria isolated from hydrazine- and ethanol- treated rat livers. Pathology International 50,20-33頁 (共著) 2000
論文	Detailed localization of photoreceptor guanylate cyclase activating protein-1 and -2 in mammalian retinas using light and electron microscopy. Experimental Eye Research 68,465-473頁 (共著) 1999
論文	Effects of coenzyme Q10 on changes in the membrane potential and rate of generation of reactive oxygen species in hydrazine- and chloramphenicol-treated rat liver mitochondria. Archives of Biochemistry and Biophysics 366 (1),157-167頁 (共著) 1999
論文	Free radical-induced megamitochondria formation and apoptosis. Free Radical Biology and Medicine 26,396-409頁 (共著) 1999
論文	Identification of the Hemidesmosomal 500 kDa Protein (HD1) as Plectin. Journal of Biochemistry 126,1144-1150頁 (共著) 1999
論文	Initiating ocular proteomics for cataloging retinal proteins: Microanalytical techniques permit the identification of proteins derived from a novel photoreceptor preparation. Experimental Eye Research 69,195-212頁 (共著) 1999
論文	Rapid making a photoreceptor protein catalogue using mass spectrometry. Journal of the Mass Spectrometry Society of Japan 47 (3),177-182頁 (共著) 1999
論文	A possible role of RGS9 in phototransduction. Journal of Biological Chemistry 273 (35),22169-22172頁 (共著) 1998
論文	Identification of a novel nuclear speckle-type protein, SPOP. FEBS Letters 418,23-26頁 (共著) 1997
論文	Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocyes. Biochimica et Biophysica ACTA/General Subjects 1349,242-250頁 (共著) 1997
論文	Demonstration of the molecular shape of BP180, a 180-kDa bullous pemphigoid antigen and its potential for trimer formation. Journal of Biological Chemistry 271,13739-13745頁 (共著) 1996
論文	Mechanism of the formation of megamitochondria in the mouse liver induced by chloramphenicol. Toxicology Letters 86,47-54頁 (共著) 1996
論文	Confocal imaging of megamitochondria formation induced by ethanol and hydrazine in culture cells (RL-34). Bioimages 3,25-30頁 (共著) 1995
論文	Studies on urea synthesis in the rat liver of rats treated chronically with ethanol using perfused livers, isolated hepatocytes and mitochondria. Biochemical Pharmacology 50,1391-1399頁 (共著) 1995
論文	Suppression of the hydrazine-induced formation of megamitochondria in the rat liver by CoQ10. Toxicologic Pathology 23,667-676頁 (共著) 1995
論文	Demonstration of type II hemidesmosomes in a mammary gland epithelial cell line, BMGE-H. Journal of Biochemistry 115,469-476頁 (共著) 1994
論文	Further studies on physicochemical properties of mitochondrial membranes during the formation process of megamitochondria in the rat liver by hydrazine. Experimental Molecular Pathology 61,134-151頁 (共著) 1994
論文	Suppression of the hydrazine-induced formation of megamitochondria in the rat liver by alpha-tocopherol. Experimental Molecular Pathology 60,173-187頁 (共著) 1994
論文	Ultrastructural localization of retinal guanylate cyclase in human and monkey retina. Experimental Eye Research 59,761-768頁 (共著) 1994
論文	HD4, a 180 kDa bullous pemphigoid antigen, is a major transmembrane glycoprotein of the hemidesumosome. J. Biochem. 113,493-501頁 (共著) 1993
論文	Three-demensional imaging of the cytoskeletal organization of actin filaments in rod photoreceptor cells. Bioimages 1 (2),181-187頁 (共著) 1993
論文	Control of the distribution of hemidesmosome components in cultured keratinocytes: Ca2+ and phorbol esters. Journal of Dermatology 19 (11),770-773頁 (共著) 1992
論文	Phorbol ester- and calcium-induced reorganization of 180-kDa bullous pemphigoid antigen on the ventral surface of cultured human keratinocytes as studied by immunofluorescence and immunoelectron microscopy. Exerimental Cell Research 203 (1),17-24頁 (共著) 1992
論文	Isolation and characterization of hemidesmosomes from bovine corneal epithelial cells. Experimental Cell Research 192 (2),622-630頁 (共著) 1991