Faculty
JAPANESE
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SOBUE Sayaka
Department / Course
Office for the Coordination of Clinical Practicums Center for Clinical Examination Practicum Support
College of Life and Health Sciences Department of Biomedical Sciences
Center for Mathematical Science and Artificial Intelligence
Job
Associate Professor
Book and thesis
Papers
Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study Med Gas Res. 10,pp.163 (Co-authored) 2020
Papers
BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells. Biochem Biophys Rep. 15,pp.69 (Co-authored) 2018
Papers
Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. Clin Exp Hypertens. 14,pp.1 (Co-authored) 2018
Papers
Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles: meta-analyses of gene expression profiles. Free Radic Res. 20,pp.1 (Co-authored) 2018
Papers
Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. Biochem Biophys Res Commun 493,pp.318-324 (Co-authored) 2017
Papers
Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel. Biochem Biophys Res Commun 479,pp.808-813 (Co-authored) 2016
Papers
Characterization of gene expression profiling of mouse tissues obtained during the postmortem interval. Exp Mol Pathol. 100,pp.482-492 (Co-authored) 2016
Papers
Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells. Biochem Biophys Res Commun. 470,pp.851 (Co-authored) 2016
Papers
Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles. Med Gas Res. 5,pp.12 (Co-authored) 2015
Papers
Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents. Mol Cell Biochem. 403,pp.231-241 (Co-authored) 2015
Papers
UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6. Biochem Biophys Res Commun. 445,pp.504 (Co-authored) 2014
Papers
Detection of a soluble form of CD109 in serum of CD109 transgenic and tumor xenografted mice. PLoS One. 9,pp.e83385 (Co-authored) 2014
Papers
Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB. Biochim Biophys Acta. 1833,pp.1006 (Co-authored) 2013
Papers
Epidermal Hyperplasia and Appendage Abnormalities in Mice Lacking CD109. Am J Pathol. 181,pp.1180 (Co-authored) 2012
Papers
Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7. J Biochem. 151,pp.599 (Co-authored) 2012
Papers
Analysis of the pathological lesions of the lung in a mouse model of cutaneous infection with Streptococcus pyogenes. Pathol Int. 62,pp.99 (Co-authored) 2012
Papers
Sphingosine Kinase 1/S1P Pathway Involvement in the GDNF-Induced GAP43 Transcription. J Cell Biochem. 112,pp.3449 (Co-authored) 2011
Papers
Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines. Biochim Biophys Acta. 1811,pp.119 (Co-authored) 2011
Papers
ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells: the role of COUP-TFI. J Neurochem. 112,pp.511 (Co-authored) 2010
Papers
Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin. Biochim Biophys Acta. 1789,pp.681 (Co-authored) 2009
Papers
GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines. Leukemia. 23,pp.1270 (Co-authored) 2009
Papers
v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins. Oncogene. 27,pp.6023-6033 (Co-authored) 2008
Papers
Characterization of myelodysplastic syndrome and aplastic anemia by immunostaining of p53 and hemoglobin F and karyotype analysis: differential diagnosis between refractory anemia and aplastic anemia. Pathol Int. 58,pp.353 (Co-authored) 2008
Papers
Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells. Int J Hematol. 87,pp.266-275 (Co-authored) 2008
Papers
RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis J Neurochem. 102,pp.1585 (Co-authored) 2007
Papers
Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes. FEBS Lett. 581,pp.1800 (Co-authored) 2007
Papers
Quantitative RT-PCR analysis of sphingolipid metabolic enzymes in acute leukemia and myelodysplastic syndromes. Leukemia. 20,pp.2042-2046 (Co-authored) 2006
Papers
Ewing’s sarcoma fusion protein, EWS/Fli-1 protein induce PLD2 but not PLD1 gene expression by binding to an ETS domain of 5’ promoter. Oncogene 26,pp.1802 (Co-authored) 2007
Papers
Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12. J Neurochem. 95,pp.940-949 (Co-authored) 2005
Papers
Sphingosine kinase 1 is involved indibutyryl cyclic AMP-induced granulocytic differentiation through the upregulation of extracellular signal-regulated kinase, but not p38 MAP kinase, in HL60 cells. Biochim. Biophys Acta. 1733,pp.101 (Co-authored) 2005
Papers
Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1. Biochim. Biophys Acta. 1635,pp.104 (Co-authored) 2003
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