教員情報
ENGLISH
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ソブエ サヤカ
SOBUE Sayaka
祖父江 沙矢加
所属
臨地実習推進部 臨床検査技術教育・実習センター
生命健康科学部 生命医科学科
AI数理データサイエンスセンター
職名
准教授
著書・論文歴
論文
Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study Med Gas Res. 10,163 (共著) 2020
論文
Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes Nagoya J Med Sci 82 (261) (共著) 2020
論文
Involvement of MCL1, C-Myc, and Cyclin D2 Protein Degradation in Ponatinib-Induced Cytotoxicity Against T315I(+) Ph+leukemia Cells Biochem Biophys Res Commun 14,1074 (共著) 2020
論文
BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells. Biochem Biophys Rep. 15,69 (共著) 2018
論文
Hydrogen gas improves left ventricular hypertrophy in Dahl rat of salt-sensitive hypertension. Clin Exp Hypertens. 14,1 (共著) 2018
論文
Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles: meta-analyses of gene expression profiles. Free Radic Res. 20,1 (共著) 2018
論文
Molecular hydrogen modulates gene expression via histone modification and induces the mitochondrial unfolded protein response. Biochem Biophys Res Commun 493,318-324頁 (共著) 2017
論文
Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR. Biochem Biophys Res Commun. 486 (551) (共著) 2017
論文
Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel. Biochem Biophys Res Commun 479,808-813頁 (共著) 2016
論文
Characterization of gene expression profiling of mouse tissues obtained during the postmortem interval. Exp Mol Pathol. 100,482-492頁 (共著) 2016
論文
分子状水素によるマウス肝臓における遺伝子発現変化の解析 中部大学生命健康科学研究所紀要 12,38 (共著) 2016
論文
Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells. Biochem Biophys Res Commun. 470,851 (共著) 2016
論文
Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles. Med Gas Res. 5,12 (共著) 2015
論文
Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents. Mol Cell Biochem. 403,231-241頁 (共著) 2015
論文
Photoshopを用いた画像解析の検討 社団法人 愛知県臨床衛生検査技師会誌 らぼ 65 (1) (共著) 2014
論文
UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6. Biochem Biophys Res Commun. 445,504 (共著) 2014
論文
Detection of a soluble form of CD109 in serum of CD109 transgenic and tumor xenografted mice. PLoS One. 9,e83385 (共著) 2014
論文
分子状水素の生体作用-過去6年間で何が明らかとなったか- 安定同位体と生体ガス 5 (4) (共著) 2013
論文
Sphingosine kinase 1 expression is downregulated during differentiation of Friend cells due to decreased c-MYB. Biochim Biophys Acta. 1833,1006 (共著) 2013
論文
Epidermal Hyperplasia and Appendage Abnormalities in Mice Lacking CD109. Am J Pathol. 181,1180 (共著) 2012
論文
Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7. J Biochem. 151,599 (共著) 2012
論文
Analysis of the pathological lesions of the lung in a mouse model of cutaneous infection with Streptococcus pyogenes. Pathol Int. 62,99 (共著) 2012
論文
Sphingosine Kinase 1/S1P Pathway Involvement in the GDNF-Induced GAP43 Transcription. J Cell Biochem. 112,3449 (共著) 2011
論文
Heterogeneous sphingosine-1-phosphate lyase gene expression and its regulatory mechanism in human lung cancer cell lines. Biochim Biophys Acta. 1811,119 (共著) 2011
論文
ATRA inhibits ceramide kinase transcription in a human neuroblastoma cell line, SH-SY5Y cells: the role of COUP-TFI. J Neurochem. 112,511 (共著) 2010
論文
Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin. Biochim Biophys Acta. 1789,681 (共著) 2009
論文
分子状水素の臨床応用に向けた研究の現状について 生命健康科学研究所紀要 5 (37) (共著) 2009
論文
GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines. Leukemia. 23,1270 (共著) 2009
論文
v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins. Oncogene. 27,6023-6033頁 (共著) 2008
論文
Characterization of myelodysplastic syndrome and aplastic anemia by immunostaining of p53 and hemoglobin F and karyotype analysis: differential diagnosis between refractory anemia and aplastic anemia. Pathol Int. 58,353 (共著) 2008
論文
Implications of sphingosine kinase 1 expression level for the cellular sphingolipid rheostat: relevance as a marker for daunorubicin sensitivity of leukemia cells. Int J Hematol. 87,266-275頁 (共著) 2008
論文
RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis J Neurochem. 102,1585 (共著) 2007
論文
Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes. FEBS Lett. 581,1800 (共著) 2007
論文
Quantitative RT-PCR analysis of sphingolipid metabolic enzymes in acute leukemia and myelodysplastic syndromes. Leukemia. 20,2042-2046頁 (共著) 2006
論文
Ewing’s sarcoma fusion protein, EWS/Fli-1 protein induce PLD2 but not PLD1 gene expression by binding to an ETS domain of 5’ promoter. Oncogene 26,1802 (共著) 2007
論文
Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12. J Neurochem. 95,940-949頁 (共著) 2005
論文
Sphingosine kinase 1 is involved indibutyryl cyclic AMP-induced granulocytic differentiation through the upregulation of extracellular signal-regulated kinase, but not p38 MAP kinase, in HL60 cells. Biochim. Biophys Acta. 1733,101 (共著) 2005
論文
Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1. Biochim. Biophys Acta. 1635,104 (共著) 2003
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