教員情報 - 古川　圭子 | 中部大学

フルカワ　ケイコ FURUKAWA Keiko
古川　圭子

所属

生命健康科学部生命医科学科

臨地実習推進部臨床検査技術教育・実習センター

大学院生命健康科学研究科生命医科学専攻

職名教授

著書・論文歴
論文	Cis glycan–glycan interactions organize membrane nanodomains that tune receptor signaling Nature Communications 17 (8813),1-25頁 (共著) 2026/08
論文	Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin. 224 (6) (共著) 2025/04
論文	GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics. 116 (4),862-870頁 (共著) 2025/02
論文	Action mechanisms of exosomes derived from GD3/GD2-positive glioma cells in the regulation of phenotypes and intracellular signaling: Roles of integrins. Int J Mol Sci. 25(23),12752 (共著) 2024/11
論文	Bidirectional signals generated by Siglec-7 and the crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance. iScience 27(11):111139 (共著) 2024/10
論文	Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells. Nagoya J Med. Sci. (共著) 2024/08
論文	The lipid globotriaosylceramide promotes germinal center B cell responses and antiviral immunity. Science 383(6684):eadg0564. (共著) 2024/02
論文	Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance malignant properties of GD2-negative melanomas. Sci. Rep. (共著) 2023/03
論文	Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway. PLoS ONE 18(2):e0281414. (共著) 2023/02
論文	Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins. Int. J. Mol. Sci. (共著) 2021/12
論文	TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes. Sci Rep. (共著) 2019/10
論文	Differential roles of gangliosides in malignant properties of melanomas. PLoS One (共著) 2018/11
論文	UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6. Biochem. Biophys. Res. Commun. (共著) 2014/03
論文	Ganglioside GD3 induces convergence and synergism of adhesion- and hepatocyte growth factor/Met-signals in melanomas. Cancer Sci. (共著) 2013/12
論文	Functional activation of Src family kinase Yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3. J. Biol. Chem. (共著) 2011/03
論文	Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains. J. Biol. Chem. (共著) 2010/06
論文	Ganglioside GD3 Promotes Cell Grouth and Invasion through p130 Cas and Paxillin in Malignan Melanoma Cells Proc Natl Acad Sci USA. (共著) 2005/07