教員情報 - 川本　善之

カワモト　ヨシユキ KAWAMOTO Yoshiyuki
川本　善之

所属

生命健康科学部生命医科学科

臨地実習推進部臨床検査技術教育・実習センター

大学院生命健康科学研究科生命医科学専攻

国際・地域戦略部門地域連携教育センター

職名准教授

著書・論文歴
論文	A novel synthetic melanin as a potential anticancer agent that induces apoptosis and cyclin D downregulation through distinct pathways. The Journal of biological chemistry,113065-113065頁 (共著) 2026/04/24
論文	Action Mechanisms of Exosomes Derived from GD3/GD2-Positive Glioma Cells in the Regulation of Phenotypes and Intracellular Signaling: Roles of Integrins. International journal of molecular sciences 25 (23) (共著) 2024/11/27
論文	Increased serum anti-CYP2E1 IgG autoantibody levels may be involved in the pathogenesis of occupational trichloroethylene hypersensitivity syndrome: a case-control study. Archives of toxicology 96 (10),2785-2797頁 (共著) 2022/10
論文	CEBPγ facilitates lamellipodia formation and cancer cell migration through CERS6 upregulation. Cancer science 112 (7),2770-2780頁 (共著) 2021/07
論文	The combination therapy of targeting both paclitaxel and Dendrophthoe pentandra leaves extract nanoparticles for improvement breast cancer treatment efficacy by reducing TUBB3 and MAP4 expressions Acta Biochim Pol (共著) 2021/07
論文	Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells. Biochemical and biophysical research communications 525 (4),1074-1080頁 (共著) 2020/05/14
論文	Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes. Nagoya journal of medical science 82 (2),261-280頁 (共著) 2020/05
論文	Oxidized Perilla and Linseed Oils Induce Neuronal Apoptosis by Caspase-Dependent and -Independent Pathways Foods 9 (5),538-538頁 (共著) 2020/04/26
論文	Peptides containing the MXXCW motif inhibit oncogenic RET kinase activity with a novel mechanism of action. American journal of cancer research 10 (1),336-349頁 (共著) 2020/01
論文	Inhibition of mast cell degranulation by melanin. Biochemical pharmacology 163,178-193頁 (共著) 2019/05
論文	Myonectin Is an Exercise-Induced Myokine That Protects the Heart From Ischemia-Reperfusion Injury. Circulation research 123 (12),1326-1338頁 (共著) 2018/12/07
論文	BCL2 inhibitor ABT-199 and JNK inhibitor SP600125 exhibit synergistic cytotoxicity against imatinib-resistant Ph+ ALL cells. Biochemistry and biophysics reports 15,69-75頁 (共著) 2018/09
論文	Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR. Biochemical and biophysical research communications 486 (2),551-557頁 (共著) 2017/04/29
論文	Morphological analyses in fragility of pili torti with Björnstad syndrome. The Journal of dermatology 44 (4),455-458頁 (共著) 2017/04
論文	Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel. Biochemical and biophysical research communications 479 (4),808-813頁 (共著) 2016/10/28
論文	Resveratrol-induced transcriptional up-regulation of ASMase (SMPD1) of human leukemia and cancer cells. Biochemical and biophysical research communications 470 (4),851-6頁 (共著) 2016/02/19
論文	Prevention of allergic rhinitis by ginger and the molecular basis of immunosuppression by 6-gingerol through T cell inactivation. The Journal of nutritional biochemistry 27,112-22頁 (共著) 2016/01
論文	Increased SPHK2 Transcription of Human Colon Cancer Cells in Serum-Depleted Culture: The Involvement of CREB Transcription Factor. Journal of cellular biochemistry 116 (10),2227-38頁 (共著) 2015/10
論文	Commentary to Pastore et al. (2014): epidermal growth factor receptor signaling in keratinocyte biology: implications for skin toxicity of tyrosine kinase inhibitors. Archives of toxicology 88 (12),2319-20頁 (共著) 2014/12
論文	Isolation of a hemidesmosome-rich fraction from a human squamous cell carcinoma cell line. Experimental cell research 324 (2),172-82頁 (共著) 2014/06/10
論文	A case of Björnstad syndrome caused by novel compound heterozygous mutations in the BCS1L gene. The British journal of dermatology 170 (4),970-973頁 (共著) 2014/04
論文	Actin-binding protein, Espin: a novel metastatic regulator for melanoma. Molecular cancer research : MCR 12 (3),440-6頁 (共著) 2014/03
論文	Molecular Network Associated with MITF in Skin Melanoma Development and Progression. Journal of skin cancer 2011,730170-730170頁 (共著) 2011/10
論文	RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy. Dermatology research and practice 2012,354191-354191頁 (共著) 2011/10
論文	Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury. Neurobiology of disease 43 (3),706-14頁 (共著) 2011/09
論文	Control of genetically prescribed protein tyrosine kinase activities by environment-linked redox reactions. Enzyme research 2011,896567-896567頁 (共著) 2011/06
論文	Protective role of Gipie, a Girdin family protein, in endoplasmic reticulum stress responses in endothelial cells. Molecular biology of the cell 22 (6),736-47頁 (共著) 2011/03/15
論文	A redox-linked novel pathway for arsenic-mediated RET tyrosine kinase activation. Journal of cellular biochemistry 110 (2),399-407頁 (共著) 2010/05/15
論文	1,4-butanediyl-bismethanethiosulfonate (BMTS) induces apoptosis through reactive oxygen species-mediated mechanism. Journal of cellular biochemistry 108 (5),1059-65頁 (共著) 2009/12/01
論文	Bid truncation mediated by caspases-3 and-9 in vinorelbine-induced apoptosis APOPTOSIS 13 (4),523-530頁 (共著) 2008/04
論文	Protective effect of hyperpigmented skin on UV-mediated cutaneous cancer development JOURNAL OF INVESTIGATIVE DERMATOLOGY 127 (5),1244-1249頁 (共著) 2007/05
論文	Novel hairless RET-transgenic mouse line with melanocytic nevi and anagen hair follicles JOURNAL OF INVESTIGATIVE DERMATOLOGY 126 (11),2547-2550頁 (共著) 2006/11
論文	細胞膜脂質ラフトを介する活性酸素種産生機序の解析生活習慣病予防をめざして中部大学生命健康科学研究所紀要 2,1-6頁 (単著) 2006/03
論文	A PKC-mediated backup mechanism of the MXXCW motif-linked switch for initiating tyrosine kinase activities FEBS LETTERS 580 (3),839-843頁 (共著) 2006/02
論文	【癌の漢方療法新しい展開】十全大補湯による腫瘍特異的細胞傷害性T細胞の誘導 Biotherapy 20 (1),33-39頁 (共著) 2006/01
論文	Cutting edge: CD8(+)CD122(+) regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8(+) T cells JOURNAL OF IMMUNOLOGY 175 (11),7093-7097頁 (共著) 2005/12
論文	レドックス制御による細胞膜関連チロシンキナーゼの活性化中部大学生命健康科学研究所紀要 1,17-24頁 (共著) 2005/03
論文	Redox control of catalytic activities of membrane-associated protein tyrosine kinases ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 434 (1),3-10頁 (共著) 2005/02
論文	Essential roles of CD8(+)CD122(+) regulatory T cells in the maintenance of T cell homeostasis JOURNAL OF EXPERIMENTAL MEDICINE 200 (9),1123-1134頁 (共著) 2004/11
論文	Inhibition of Fas-mediated apoptotic cell death of murine T lymphocytes in a mouse model of immunosenescence in linkage to deterioration in cell membrane raft function IMMUNOLOGY 112 (1),64-71頁 (共著) 2004/05
論文	Identification of RET autophosphorylation sites by mass spectrometry JOURNAL OF BIOLOGICAL CHEMISTRY 279 (14),14213-14224頁 (共著) 2004/04
論文	c-Kit-targeting immunotherapy for hereditary melanoma in a mouse model CANCER RESEARCH 64 (3),801-806頁 (共著) 2004/02
論文	Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12),(14)-prostaglandin J(2) MOLECULAR AND CELLULAR BIOLOGY 24 (1),36-45頁 (共著) 2004/01
論文	4-Hydroxynonenal triggers multistep signal transduction cascades for suppression of cellular functions Molecular Aspects of Medicine 24 (4-5),231-238頁 (共著) 2003/08
論文	Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal CELL DEATH AND DIFFERENTIATION 10 (7),772-781頁 (共著) 2003/07
論文	Transgenic mouse models for immunosenescence Current Genomics 4 (5),435-443頁 (共著) 2003/07
論文	Caspase activation is accelerated by the inhibition of arsenite-induced, membrane rafts-dependent Akt activation FREE RADICAL BIOLOGY AND MEDICINE 34 (5),598-606頁 (共著) 2003/03
論文	Redox-linked signal transduction pathways for protein tyrosine kinase activation ANTIOXIDANTS & REDOX SIGNALING 4 (3),517-531頁 (共著) 2002/06
論文	Activation of caspase-8 is critical for sensitivity to cytotoxic anti-Fas anti body-induced apoptosis in human ovarian cancer cells APOPTOSIS 7 (2),107-113頁 (共著) 2002/04
論文	Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine CANCER RESEARCH 62 (8),2414-2422頁 (共著) 2002/04
論文	RET tyrosine kinase enhances hair growth in association with promotion of melanogenesis ONCOGENE 20 (51),7536-7541頁 (共著) 2001/11
論文	T-cell-immunity-based inhibitory effects of orally administered herbal medicine juzen-taiho-to on the growth of primarily developed melanocytic tumors in RET-transgenic mice JOURNAL OF INVESTIGATIVE DERMATOLOGY 117 (3),694-701頁 (共著) 2001/09
論文	Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells FREE RADICAL BIOLOGY AND MEDICINE 31 (1),20-30頁 (共著) 2001/07
論文	4-Hydroxy-2-nonenal is a powerful endogenous inhibitor of endothelial response Biochemical and Biophysical Research Communications 282 (2),557-561頁 (共著) 2001/03/30
論文	4-hydroxy-2-nonenal, the end product of lipid peroxidation, is a specific inducer of cyclooxygenase-2 gene expression BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 273 (2),437-441頁 (共著) 2000/07
論文	Cyclopentenone prostaglandins as potential inducers of phase II detoxification enzymes - 15-deoxy-Delta(12,14)-prostaglandin J2-induced expression of glutathione S-transferases JOURNAL OF BIOLOGICAL CHEMISTRY 275 (15),11291-11299頁 (共著) 2000/04
論文	Molecular mechanism of activation and superactivation of Ret tyrosine kinases by ultraviolet light irradiation Antioxidants and Redox Signaling 2 (4),841-849頁 (共著) 2000/02
論文	Redox regulation of glutathione S-transferase induction by benzyl isothiocyanate: Correlation of enzyme induction with the formation of reactive oxygen intermediates CANCER RESEARCH 60 (2),219-225頁 (共著) 2000/01