教員情報 - 堤内　要

ツツミウチ　カナメ TSUTSUMIUCHI Kaname
堤内　要

所属応用生物学部応用生物化学科

大学院応用生物学研究科応用生物学専攻

先端研究センター

職名教授

著書・論文歴
著書	プラスチック社会を考える産官学民によるSDGs都市づくりに向けて (共著) 2020/12/20
著書	第4版マクマリー生物有機化学基礎化学編 (共著) 2015/01
著書	食品安全の事典 2009
著書	第2版マクマリー生物有機化学基礎化学編 (共著) 2007/01
著書	Syntheses and Functions of Glycopeptide Surface-Modified Dendrimers(共著) 2000
論文	クチナシ青色素の共鳴構造に関する考察：従来の共鳴混成体の概念から逸脱した特異な共鳴挙動食品衛生学雑誌 66 (1),J-1-J-5頁 (単著) 2025/02/25
論文	日本固有種”甲州”と”マスカット・ベーリーA”が織りなすワインの魅力を世界へアグリバイオ 8 (7),74-80頁 (共著) 2024/07/20
論文	Recovery of extracellular vesicles from liquid samples using polyamine solution Medical Mass Spectrometry 8 (1),35-42頁 (共著) 2024/06/05
論文	In Vitro Study of Tumor-Homing Peptide-Modified Magnetic Nanoparticles for Magnetic Hyperthermia Molecules 29 (1),2632-42頁 (共著) 2024/06/03
論文	放射線から簡便に発電する方法を開発放射線化学 117 (1),3-6頁 (単著) 2024/04/30
論文	日本古来のぶどう“甲州”の魅力を引き出す―日本の甲州葡萄酒から世界の Koshu wine へ― アグリバイオ 7 (3),260-264頁 2023/03/20
論文	Preparation of Functional Nanoparticles-Loaded Magnetic Carbon Nanohorn Nanocomposites towards Composite Treatment. Nanomaterials (Basel, Switzerland) 13 (5) 2023/02/23
論文	Role of HIKESHI on Hyperthermia for Castration-Resistant Prostate Cancer and Application of a Novel Magnetic Nanoparticle with Carbon Nanohorn for Magnetic Hyperthermia. Pharmaceutics 15 (2) 2023/02/13
論文	Direct chiral separation of abscisic acid by high‐performance liquid chromatography with a phenyl column and a mobile phase containing γ‐cyclodextrin Journal of Separation Science 46 (6) 2023/01/31
論文	新しいアロマを持つ上質な甲州ワイン醸造をめざして―ウイルス非感染甲州ブドウの果汁成分解析アグリバイオ 6 (10),973-977頁 2022/09/20
論文	磁性ナノ粒子用がん温熱療法小型装置の試作とスケール則によるヒト用大型装置の検討電気学会論文誌C（電子・情報・システム部門誌） 142 (5),506-512頁 2022/05
論文	Drug Release Stimulated by Magnetic Field and Light on Magnetite- and Carbon Dot-Loaded Carbon Nanohorn Bulletin of the Chemical Society of Japan 95 (4),582-594頁 2022/04
論文	Establishment of the optimal condition for shoot regeneration in Vitis vinifera 'Koshu' Annual Report of Research Institute for Biological Function (Chubu University) 22,48-56頁 2022/03
論文	ウイルス非感染甲州ブドウ樹の作製と新しいアロマをもつ上質な甲州ワイン醸造を目指してアグリバイオ 6 (3),87-90頁 2022/03
論文	カルボニル基を含む溶媒によるアモルファス PET フィルムの結晶化中部大学工学部紀要 57,37-41頁 2022/03
論文	重水素化エボジアミンの合成とLC-MS/MSによるエボジアミン定量への応用生物機能開発研究所紀要 22,38-47頁 2022/03
論文	LC-MS/MS assay for the investigation of acetylated Alpha-synuclein in serum from postmortem Alzheimer's disease pathology. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 1181,122885-122885頁 2021/08/28
論文	Molecular Structure of Gardenia Blue Pigments by Reaction of Genipin with Benzylamine and Amino Acids Journal of Agricultural and Food Chemistry 69 (13),3904-3911頁 2021/03
論文	Production of Virus-free Vitis Vinifera ‘koshu’ Plantlets From Shoot Tips or Axillary Buds Research Square 2020/11/13
論文	Modeling of Innovation Research Clusters in the Field of Radioactive Waste Utilization JOURNAL OF ENGINEERING SCIENCES 7 (2),H1-H9頁 2020/10
論文	酢酸エチルにより溶媒結晶化させたポリエチレンテレフタレート・ペレットを用いた射出成形品の強度増加の発見中部大学工学部紀要 55,29-31頁 2020/03
論文	ゲムシタビン内包型マグネタイト結合単層カーボンナノホーンを用いた磁場照射による尿路上皮癌に対する温熱化学療法の開発 Thermal Medicine 35 (Suppl.),116-116頁 2019/09
論文	ゲムシタビン内包型マグネタイト結合単層カーボンナノホーンを用いた磁場照射による泌尿器系癌に対する温熱化学療法の開発日本泌尿器科学会総会 107回,PP2-350頁 2019/04
論文	エクトインの重水素化による安定同位元素標識化合物の調製生物機能開発研究所紀要 19,87-93頁 2019/03
論文	Solvent crystallization and Heat Resistance of amorphous PET film with ethyl acetate Transactions of the Materials Research Society of Japan 44,25-28頁 2019/02
論文	Identification of evodiamine in the microalga Dunaliella tertiolecta (Chlorophyceae) New Food Industry 60 (10),13-18頁 2018/10
論文	膀胱癌に対するMagnetic Cationic Liposomeを用いた新規温熱治療の開発のための基礎研究-第1報 Thermal Medicine 34 (3),129-130頁 2018/09
論文	6-および7-ホスホノメチルナフタレン-1-カルボン酸の化学合成生物機能開発研究所紀要 18,62-69頁 2018/03
論文	Analysis of gardenia blue in foods by thin-layer chromatography Journal of Liquid Chromatography and Related Technologies 41 (2),83-86頁 2018/01/20
論文	Effect of crystal status transformation on the thermal shrinkage characteristics and extensional characteristics of acetaldehyde solvent-induced crystalization PET film Transactions of the Materials Research Society of Japan 42,107-111頁 2017/11
論文	Safety of Regional 8-MHz Radiofrequency Capacitive Hyperthermia Combined with Magnetic Cationic Liposomes in Patients with Castration-Resistant Prostate Cancer: A Phase I Clinical Study Journal of International Translational Medicine 4,258-267頁 2016/12
論文	去勢抵抗性前立腺がんを対象としたマグネタイト微粒子と誘電加温装置「RF-8」を用いた新規温熱治療の第I相臨床試験 Thermal Medicine 32 (3),89-89頁 2016/09
論文	去勢抵抗性前立腺がんを対象としたマグネタイト微粒子と誘電加温装置を用いた新規温熱治療の第1相臨床試験 Thermal Medicine 32 (Suppl.),73-73頁 2016/09
論文	Dietary supplementation with evodiamine prevents obesity and improves insulin resistance in ageing mice JOURNAL OF FUNCTIONAL FOODS 19,320-329頁 2015/12
論文	Simultaneous Determination of Trigonelline, Caffeine, Chlorogenic Acid and Their Related Compounds in Instant Coffee Samples by HPLC Using an Acidic Mobile Phase Containing Octanesulfonate ANALYTICAL SCIENCES 31 (8),831-835頁 2015/08
論文	Simultaneous Determination of Post-Translational Racemization and Isomerization of N-Terminal Amyloid-beta in Alzheimer’s Brain Tissues by Covalent Chiral Derivatized Ultraperformance Liquid Chromatography Tandem Mass Spectrometry Analytical Chemistry 86 (1),797-804頁 2013/11
論文	Macrophage Migration Inhibitory Factor and Stearoyl-CoA Desaturase 1: Potential Prognostic Markers for Soft Tissue Sarcomas Based on Bioinformatics Analyses PLOS ONE 8 (10),e78250 2013/10
論文	DEVELOPMENT OF AN ANTICANCER HYPERTHERMIC THERAPY FOR BONE-SPECIFIC METASTASIS IN PROSTATE CANCER BY USING ANTI-RANKL ANTIBODY-CONJUGATED MAGNETIC NANOPARTICLES JOURNAL OF UROLOGY 189 (4),E207-E207頁 2013/04
論文	N-ビニル-2-ピロリドン/メタクリル酸メチル/メタクリル酸三元共重合体被覆マグネタイトナノ粒子の調製と特性解析高分子論文集 69 (7),392-398頁 2012/07
論文	On-line solid-phase extraction LC-MS/MS for the determination of Ac-SDKP peptide in human plasma from hemodialysis patients BIOMEDICAL CHROMATOGRAPHY 26 (2),137-141頁 2012/02
論文	Formation of acrylamide from glucans and asparagine NEW BIOTECHNOLOGY 28 (6),566-573頁 2011/10
論文	Quantification of N-acetyl-seryl-aspartyl-lysyl-proline in hemodialysis patients administered angiotensin-converting enzyme inhibitors by stable isotope dilution liquid chromatography-tandem mass spectrometry JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 54 (4),765-771頁 2011/03
論文	Efficient purification of xanthomonasin A and B from Monascus yellow colorant by high-speed countercurrent chromatography Japanese Journal of Food Chemistry and Safety 17 (3),185-191頁 2010/12
論文	Allyl Isothiocyanate that Induces GST and UGT Expression Confers Oxidative Stress Resistance on C. elegans, as Demonstrated by Nematode Biosensor PLOS ONE 5 (2),e9267 2010/02
論文	2Jp13 磁性ナノ粒子の調製と抗体結合(生体医用工学・人工臓器,一般講演) 日本生物工学会大会講演要旨集 21,144-144頁 2009
論文	Determination of avoparcin in animal tissues and milk using LC-ESI-MS/MS and tandem-SPE JOURNAL OF SEPARATION SCIENCE 31 (22),3871-3878頁 2008/12
論文	Acrylamide-responsive genes in the nematode Caenorhabditis elegans TOXICOLOGICAL SCIENCES 101 (2),215-225頁 2008/02
論文	Separation of major safflowers from Carthamus yellow using high-speed countercurrent chromatography JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES 31 (7),1047-1059頁 2008
論文	A rapid and inexpensive method to screen for common foods that reduce the action of acrylamide, a harmful substance in food TOXICOLOGY LETTERS 175 (1-3),82-88頁 2007/12
論文	食品中のアクリルアミド生物機能開発研究所紀要（中部大学） 7,7-12頁 2007/03
論文	加工食品中のアクリルアミドモノマーの低減化法について食品衛生学雑誌 46 (6),J-335-J-337 2005/12
論文	Effect of Carbohydrates on Formation of Acrylamide in Cooked Food Models Journal of applied glycoscience 52 (3),219-224頁 2005/07
論文	Extremely low dose of acrylamide decreases lifespan in Caenorhabditis elegans TOXICOLOGY LETTERS 152 (2),183-189頁 2004/09
論文	Application of ion-trap LC/MS/MS for determination of acrylamide in processed foods JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN 45 (2),95-99頁 2004/04
論文	アリル 3-O-アリル-6-O-(p-メトキシフェニル)-D-グルコピラノシドの合成（単著）中部大学応用生物学部紀要 3, 5-8 2004/03
論文	食品機能プロジェクト(生物機能開発研究所のプロジェクト研究概要) 生物機能開発研究所紀要 3,2-3頁 2003/03/31
論文	Small-angle neutron scattering investigations of layer - Block dendrimers in aqueous solutions Journal of Physical Chemistry B 107 (7),1532-1539頁 2003/02/20
論文	Fast and slow dynamics of water-soluble dendrimers consisting of amido-amine repeating units by neutron spin-echo Journal of Physical Chemistry B 107 (6),1353-1359頁 2003/02/13
論文	In situ investigation of adlayer formation and adsorption kinetics of amphiphilic surface-block dendrimers on solid substrates LANGMUIR 18 (25),9757-9764頁 2002/12
論文	<Short communication>Improved synthesis of 3-O-acetyl-2,4,6-tri-O-benzyl-α-D-glucopyranosyl chloride from allyl 3-O-allyl-2,4,6-tri-O-benzyl-D-glucopyranoside Annual report of Research Institute for Biological Function 2, 17-20,17-20頁 2002/03
論文	Controlled architecture of nano-structures based on star dendrimers KOBUNSHI RONBUNSHU 59 (12),742-752頁 2002
論文	星型デンドリマーに基づくナノ構造体の精密構築（共著）高分子論文集 59 (12),742-752頁 2002
論文	Characterizations of Sugar Ball in Solution by SANS and NSE（共著） Journal of Physical Society Japan 70 (Supplement A), 326-328 2001/12
論文	Conformation of Sugar Ball in Aqueous Solutions（共著） Activity Report on Neutron Scattering Research 2000, 261 2001/02
論文	Dynamics of Poly(amido amine) Dendrimer in Aqueous Solutions（共著） Activity Report on Neutron Scattering Research 2000, 266 2001/02
論文	Formation of organized adsorption layers by amphiphilic dendrimers COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 175 (1-2),225-234頁 2000/12
論文	SANS Analysis of a Novel Star-Shaped Dendrimer（共著） KENS Report 12, 217-218 2000/02
論文	Segment Density Profiles in Dendrimers by SANS Analysis（共著） KENS Report 12, 219-220 2000/02
論文	Ion complex formation between poly(amido amine) dendrimer HCl salt and poly(L-glutamic acid) sodium salt POLYMER JOURNAL 32 (2),107-112頁 2000
論文	Syntheses and functions of glycopeptide surface-modified dendrimers TAILORED POLYMERS & APPLICATIONS,85-96頁 2000
論文	Synthesis of a novel star-shaped dendrimer by radial-growth polymerization of sarcosine N-carboxyanhydride initiated with poly(trimethyleneimine) dendrimer MACROMOLECULAR RAPID COMMUNICATIONS 20 (7),378-382頁 1999/07
論文	Small-angle neutron scattering and surface force investigations of poly(amido amine) dendrimer with hydroxyl end groups LANGMUIR 15 (12),4076-4084頁 1999/06
論文	Intermolecular Interaction and Adsorption Properties of Poly(amido amine)Dendrimer with OH-Terminal (共著) Proceedings of Yamada Conference L Polyelectrolytes 439-442 1999/05
論文	Globular carbohydrate macromolecule "sugar balls" IV. Synthesis of dendritic nanocapsules with molecular recognition sites on periphery POLYMER JOURNAL 31 (11),935-941頁 1999
論文	Synthesis and assembly of amphiphilic tadpole-shaped block copolymers based on poly(amido amine) dendrimer POLYMER JOURNAL 31 (11),1071-1078頁 1999
論文	Globular carbohydrate macromolecule "sugar balls", 2 - Synthesis of mono(glycopeptide)-persubstituted dendrimers by polymer reaction with sugar-substituted alpha-amino acid N-carboxyanhydrides (glycoNCAs) MACROMOLECULAR RAPID COMMUNICATIONS 19 (1),5-9頁 1998/01
論文	Synthesis of glycopeptide-conjugates via ring-opening polymerization of sugar-substituted alpha-amino acid N-carboxyanhydrides (GlycoNCAs) PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES 73 (10),205-209頁 1997/12
論文	Globular carbohydrate macromolecule ''sugar balls'' .3. ''Radial-growth polymerization'' of sugar-substituted alpha-amino acid N-carboxyanhydrides (GlycoNCAs) with a dendritic initiator TETRAHEDRON 53 (45),15415-15427頁 1997/11
論文	複合糖質高分子の精密構築-シュガーボールとリビング糖ペプチド（共著）高分子論文集 54 (10),649-660頁 1997/10
論文	Synthesis of polyoxazoline-(glyco)peptide block copolymers by ring-opening polymerization of (sugar-substituted) alpha-amino acid N-carboxyanhydrides with polyoxazoline macroinitiators MACROMOLECULES 30 (14),4013-4017頁 1997/07
論文	Synthesis of Sugar-Polypeptide Conjugates（単著） Doctoral Dissertation, Nagoya University 1997/03
論文	Aggregates of peptide-containing block copolymers and their interactions with a lipase in aqueous solution MACROMOLECULAR CHEMISTRY AND PHYSICS 198 (1),89-100頁 1997/01
論文	Architectural control of carbohydrate macromolecules based on sugar balls and living glycopeptides KOBUNSHI RONBUNSHU 54 (10),649-660頁 1997
論文	First synthesis of glycopeptide macromonomers and graft-type sugar-containing polymers with glycopeptide side chains MACROMOLECULES 29 (12),4456-4458頁 1996/06
論文	Aggregate of a peptide-containing block copolymer with a lipase MACROMOLECULAR RAPID COMMUNICATIONS 17 (4),269-274頁 1996/04
論文	SYNTHESIS OF NOVEL GLYCOPEPTIDE-POLYOXAZOLINE BLOCK-COPOLYMERS BY DIRECT COUPLING BETWEEN LIVING ANIONIC AND CATIONIC POLYMERIZATION SYSTEMS MACROMOLECULAR RAPID COMMUNICATIONS 16 (10),749-755頁 1995/10
論文	Glycopeptide Synthesis by an α-Amino Acid N-Carboxyanhydride (NCA) Method: Ring-Opening Polymerization of a Sugar-Substituted NCA Macromolecules 27 (3),875-877頁 1994/05/01